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Drug ReportsPorfimer sodium
Photofrin, Photobarr(porfimer sodium)
PhotoBarr, Photofrin (porfimer sodium) is a small molecule pharmaceutical. Porfimer sodium was first approved as Photofrin on 1995-12-27. It has been approved in Europe to treat barrett esophagus.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
neoplasmsD009369
digestive system diseasesD004066
Trade Name
FDA
EMA
Photofrin
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Porfimer sodium
Tradename
Company
Number
Date
Products
PHOTOFRINPinnacle BiologicsN-020451 RX1995-12-27
1 products
Labels
FDA
EMA
Brand Name
Status
Last Update
photofrinNew Drug Application2025-01-01
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
L: Antineoplastic and immunomodulating agents
— L01: Antineoplastic agents
— L01X: Other antineoplastic agents in atc
— L01XD: Sensitizers used in photodynamic/radiation therapy
— L01XD01: Porfimer sodium
HCPCS
Code
Description
J9600
Injection, porfimer sodium, 75 mg
Clinical
Clinical Trials
51 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Barrett esophagusD001471EFO_0000280K22.7—11—13
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Non-small-cell lung carcinomaD002289——12———2
Lung neoplasmsD008175—C34.9011——12
RecurrenceD012008——11———2
Brain neoplasmsD001932EFO_0003833C7111———2
Esophageal neoplasmsD004938—C15—1——12
CarcinomaD002277—C80.011———1
NeoplasmsD009369—C8011———1
Small cell lung carcinomaD055752——11———1
GliomaD005910EFO_0000520——1———1
Phototoxic dermatitisD017484———1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Pancreatic ductal carcinomaD021441——1————1
Pancreatic neoplasmsD010190EFO_0003860C251————1
AdenocarcinomaD000230——1————1
Acinar cell carcinomaD018267——1————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common namePorfimer sodium
INNporfimer sodium
Description
Porfimer sodium, sold as Photofrin, is a photosensitizer used in photodynamic therapy and radiation therapy and for palliative treatment of obstructing endobronchial non-small cell lung carcinoma and obstructing esophageal cancer.
Classification
Small molecule
Drug classpolymers
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Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID87806-31-3
RxCUI—
ChEMBL IDCHEMBL1201481
ChEBI ID60652
PubChem CID57166
DrugBankDB00707
UNII IDM15H03K69B (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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367 adverse events reported
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